In medical biotechnology: implantation of LED lamp is pain

In the past 3 months, China's LED network has reported a nerve study on LED implanted organisms that carry light responsive proteins, which is a new concern for LED in medical and biotechnology applications. Research from the University of Washington School of medicine, found that laboratory mice implanted with LED, when the researchers used LED light stimulation reward block, disgust in the brain blocks will inadvertently also driven, which explains why drug therapy in the treatment of depression in clinical look no effect. It also opens up a follow-up study of LED lights and brain connections.

The University of Denver, however, opened the door to the successful use of wireless LED implants to open up a new pattern of experiments using the principles of light genetics. With the mouse's own energy, it drives LED lights to emit light, wirelessly remote, like a blue LED device of pepper seeds, to control nerve cells, spines, or limbs in mice.

Next, researchers at the University of DELL, Moorhouse, in Canada have made new breakthroughs in putting light channels directly on the muscles, so that even if the nerves lose their function, they can drive muscle activity.

In the near future, good news has come from the medical research on implanted LED lights.

LED lights block the pain that leads to the brain and benefit patients who need pain management

Scientists have developed a flexible, implantable device that can drive pain signals in the body and spine, which can also prevent pain from passing to the brain.

Located in the eastern United States of Saint Louis Medical School of the University of Washington and the University of Illinois at Urbana Champaign, Bana researchers said that the implanted device one day is expected to be used in different parts of the body, provide another way for transmission to the brain barrier - pain not effective in the treatment of pain.

Common senior researchers Robert? Geru (Robert W. Gereau IV IV), and director of University of Washington, is also a pain center he said: "our ultimate goal is to use this technology to treat certain regional pain, using the concept of similar" switch ", in pain signals to the brain before it is blocked."

The study was published in the online edition of Nature Biotechnology in November 9, 2015.

These mice nerve as a reaction to light the protein in the cell, the researchers hope to be able to use the LED device to drive the implanted cells, passivation pain signals, blocking the normal therapy couldn't resolve the pain, for the benefit of patients. (photo: University of Washington)

An extensible, flexible LED implant that can be attached to organs such as the heart

Jeru explained that because the device is soft and extensible, it can be implanted into the active part of the body. In previous studies, such devices were often required to be implanted and fixed to the bone.

"But when we are studying areas outside the spinal cord or the central nervous system, we need devices that can stretch and do not need to be fixed on the bone," he says."

The new device can be fixed in place with surgical sutures. As with the previous device, the extendable device is equipped with a tiny LED that drives a specific nerve cell. Jeru said he hopes to use the implant to ease pain signals, blocking pain that can not be resolved by the general treatment and benefit the patient.

The researchers implanted devices in genetically modified mice. Some of these mice have nerve cells that respond to light. To demonstrate the effect of implanted devices on pain pathways in nerve cells, the researchers used LED lights to drive the mouse's pain. As the mice pass through a specific area in the maze, the LED light in the implanted device lights up and drives the pain cells to make the mice uncomfortable. After leaving the maze, the device closes and the pain disappears. The study found that the animals quickly learned to steer clear of the area.

The experiment, if used in the old version of the light genetics device, could be difficult to implement because the old version of the device had wires that could affect the behavior of rats.

Research out of lab plans, mass production of LED implants, the birth of more relevant experiments

According to the University of Illinois Department of materials engineering, and is also the common research director John? Roger said the current micro elastic device can be fixed with suture, also may be used in the kidney, stomach, intestine, heart or other organs.

He added: "they offer a special, biocompatible platform for wireless transmission of light to almost any organ in the body."."

Roger and Geru design device, pay special attention to the future of the production into consideration, so that other researchers can use this device to conduct more in-depth study. Jeru, Roger, and Joss, associate professor in the Department of Anesthesiology at University of Washington, co founded NeuroLux, Bruchas (Michael R.), toward the goal of mass production devices.

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